Targeted Gene Silencing BRAF Synergized Photothermal Effect Inhibits Hepatoma Cell Growth Using New GAL-GNR-siBRAF Nanosystem
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چکیده
منابع مشابه
Gene silencing of TKTL1 by RNAi inhibits cell proliferation in human hepatoma cells.
We detected a strong upregulation of the mutated transketolase transcript (TKTL1) in human hepatoma cell line HepG2, whereas transketolase (TKT) and transketolase-like-2 (TKTL2) transcripts were not upregulated. We inhibited the expression of TKTL1 by RNAi in HepG2 cells. It was found that total transketolase activity was dramatically downregulated and the proliferation of cancer cells was sign...
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1 1 Distribution of this document in any form violates the copyrights of the publisher. Cosuppression, post-transcriptional gene silencing (PTGS), and virus-induced gene silencing (VIGS) all describe homology-dependent gene silencing phenomena in plants that involve what is more broadly known as RNA interference (RNAi). The study of these phenomena in plants has provided numerous key discoverie...
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ژورنال
عنوان ژورنال: Nanoscale Research Letters
سال: 2020
ISSN: 1556-276X
DOI: 10.1186/s11671-020-03340-x